Compound ID | 138

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2,3-Dihydroxybenzoic Acid (DHBA)

Class: Antibiofilm agent (iron chelator)

Spectrum of activity: Gram-negative
Details of activity: Pseudomonas aeruginosa biofilm disruption
Combined with other compounds: Yes
Institute where first reported: Department of Microbiology, University of Stellenbosch, Matieland (Stellenbosch), South Africa
Year first mentioned: 1986
Highest developmental phase: Preclinical
Development status: Active
Chemical structure(s):
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Molecular weight: 154.12
Iso. SMILES: C1=CC(=C(C(=C1)O)O)C(=O)O
InChI Key: GLDQAMYCGOIJDV-UHFFFAOYSA-N
Can. SMILES: C1=CC(=C(C(=C1)C(=O)O)O)O
InChI: InChI=1S/C7H6O4/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3,8-9H,(H,10,11)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/19
Citations:
  • http://aac.asm.org/content/58/4/2098.full
  • http://onlinelibrary.wiley.com/doi/10.1002/jobm.3620260215/abstract

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