Compound ID | 1401

Update compound information

Cipro-TMIO

Synonym(s): 1-cyclopropyl-6-fluoro-7-(4-(1,1,3,3-tetramethylisoindolin-2-yloxyl-5-carbonyl)piperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Class: Fluoroquinolone

Agent Type: Synthetic; Small molecule; Direct acting; Antibiofilm;
Spectrum of activity: Gram-positive
Mechanism of action: Unknown
Target Pathogen: Active against Staphylococcus aureus
Institute where first reported: Centre of Excellence for Free Radical Chemistry and Biotechnology, Faculty of Science and Engineering, Queensland University of Technology, Queensland
Year first mentioned: 2017
Development status: Experimental
Chemical structure(s):
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Molecular weight: 547.6
Iso. SMILES: O=C(N1CCN(C2=CC=3N(C4CC4)C=C(C(O)=O)C(=O)C3C=C2F)CC1)C5=CC=6C(C)(C)N([O])C(C)(C)C6C=C5
InChI Key: UKAKKUZZTXHGBN-UHFFFAOYSA-N
Can. SMILES: CC1(C)C2=CC=C(C=C2C(C)(C)N1[O])C(=O)N3CCN(CC3)C4=CC5=C(C=C4F)C(=O)C(=CN5C6CC6)C(=O)O
InChI: InChI=1S/C30H32FN4O5/c1-29(2)21-8-5-17(13-22(21)30(3,4)35(29)40)27(37)33-11-9-32(10-12-33)25-15-24-19(14-23(25)31)26(36)20(28(38)39)16-34(24)18-6-7-18/h5,8,13-16,18H,6-7,9-12H2,1-4H3,(H,38,39)
External links:
Citation: https://aac.asm.org/content/64/1/e01685-19

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