Compound ID | 1428

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Pyrazinamide

Class: Prodrug

Details of activity: Anti-mycobacterial drug. Effective against Mycobacterium tuberculosis
Institute where first reported: Novitium Pharma; Macleods Pharmaceuticals Limited (Approved by FDA in 2020)
Year first mentioned: 1972
Highest developmental phase: Approved by FDA in 1971
Development status: Approved
Chemical structure(s):
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Molecular weight: 123.11
Iso. SMILES: C1=CN=C(C=N1)C(=O)N
InChI Key: IPEHBUMCGVEMRF-UHFFFAOYSA-N
Can. SMILES: C1=NC=C(C(=O)N)N=C1
InChI: InChI=1S/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/1046
Guide to Pharmacology: pyrazinamide
Citations:
  • https://books.google.co.uk/books?id=aZc7AQAAQBAJ&pg=PA8&redir_esc=y#v=onepage&q&f=false
  • https://mmbr.asm.org/content/84/2/e00070-19

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