Compound ID | 1429

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Verapamil

Class: Efflux pump inhibitor (ABC family inhibitor)

Details of activity: Anti-mycobacterial drug. Effective against Mycobacterium abscessus
Year first mentioned: 1981
Chemical structure(s):
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Molecular weight: 454.6
Iso. SMILES: CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC
InChI Key: SGTNSNPWRIOYBX-UHFFFAOYSA-N
Can. SMILES: CC(C)C(CCCN(C)CCC1=CC=C(C(=C1)OC)OC)(C#N)C2=CC=C(C(=C2)OC)OC
InChI: InChI=1S/C27H38N2O4/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6/h9-12,17-18,20H,8,13-16H2,1-7H3
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/2520
Guide to Pharmacology: verapamil
Citations:
  • https://www.annualreviews.org/doi/10.1146/annurev.pa.36.040196.001113
  • https://aac.asm.org/content/63/9/e00705-19

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