Compound ID | 1440

Update compound information

AZD5099

Class: Pyrrolamide

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Effective against Gram positives and fastidious Gram negatives. Discontinued.
Institute where first reported: AstraZeneca, UK
Year first mentioned: 2011
Highest developmental phase: Phase 1
Chemical structure(s):
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Molecular weight: 548.44
Iso. SMILES: CC1=C(C(=C(N1)C(=O)N[C@@H]2CCN(C[C@@H]2OC)C3=NC(=C(S3)C(=O)O)C(=O)N[C@@H](C)COC)Cl)Cl
InChI Key: KGZHRAVDXGQUQM-WCQGTBRESA-N
Can. SMILES: C[C@@H](COC)NC(=O)C1=C(C(=O)O)SC(=N1)N2CC[C@H]([C@H](C2)OC)NC(=O)C3=C(C(=C(C)N3)Cl)Cl
InChI: InChI=1S/C21H27Cl2N5O6S/c1-9(8-33-3)24-19(30)16-17(20(31)32)35-21(27-16)28-6-5-11(12(7-28)34-4)26-18(29)15-14(23)13(22)10(2)25-15/h9,11-12,25H,5-8H2,1-4H3,(H,24,30)(H,26,29)(H,31,32)/t9-,11+,12-/m0/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/11995990
Citations:
  • https://adisinsight.springer.com/drugs/800034406
  • https://pubs.acs.org/doi/10.1021/jm500462x

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