Linezolid

Synonym(s): Zyvox

Class: Oxazolidinone

Spectrum of activity:	Gram-positive
Details of activity:	MRSA and Streptococcus
Institute where first reported:	Pfizer, USA
Year first mentioned:	1990
Highest developmental phase:	Approved by FDA in 2000
Development status:	Approved

Chemical structure(s):
Canonical SMILES:	CC(=O)NC[C@H]1CN(C2=CC=C(C(=C2)F)N3CCOCC3)C(=O)O1
Isomeric SMILES:	CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F
InChI:	InChI=1S/C16H20FN3O4/c1-11(21)18-9-13-10-20(16(22)24-13)12-2-3-15(14(17)8-12)19-4-6-23-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1
InChI Key:	TYZROVQLWOKYKF-ZDUSSCGKSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/441401

External links:
Guide to Pharmacology:	linezolid
Main Source:	https://link.springer.com/article/10.1007%2Fs40262-017-0601-x