Isoniazid

Class: Cell-wall synthesis inhibitor

Spectrum of activity:	Gram-negative
Details of activity:	Gram Negative bacilli
Institute where first reported:	CMP Pharma Inc
Year first mentioned:	1952
Highest developmental phase:	Approved by FDA in 1983
Development status:	Approved
Reason Dropped:	Other formulations were discontinued

Chemical structure(s):
Canonical SMILES:	C1=C(C=CN=C1)C(=O)NN
Isomeric SMILES:	C1=CN=CC=C1C(=O)NN
InChI:	InChI=1S/C6H7N3O/c7-9-6(10)5-1-3-8-4-2-5/h1-4H,7H2,(H,9,10)
InChI Key:	QRXWMOHMRWLFEY-UHFFFAOYSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/3767

External links:
Guide to Pharmacology:	isoniazid
Main Source:	https://aac.asm.org/content/64/2/e01899-19
Citations:	https://pubmed.ncbi.nlm.nih.gov/14903503/ https://science.sciencemag.org/content/116/3006/129?ijkey=ce98bdac10b3ec52eb42daf76249fa3d06894de3&keytype2=tf_ipsecsha