Compound ID | 1453

Update compound information

Redx03863

Class: null

Agent Type: Synthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-positive, Gram-negative & Antimycobacterial
Mechanism of action: DNA synthesis inhibitor. Bacterial topoisomerase inhibitor
Target Pathogen: Broad spectrum activity including against Mycobacterium smegmatis
Institute where first reported: Norwich Research Park, Uk
Year first mentioned: 2020
Highest development stage: Preclinical
Development status: Experimental
Chemical structure(s):
Click here for structure editor
Molecular weight: 436.49
Iso. SMILES: CC=1N=CC(=CN1)OC2=NC3=C(C(N4C[C@]5([C@H](N)[C@@]5(C)C4)[H])=N2)C6=CC(F)=CC(NC)=C6N3.[H][H]
InChI Key: VGYBIYMDKFCPMQ-RGTJFBPVSA-N
Can. SMILES: CC1=NC=C(C=N1)OC2=NC(=C3C4=CC(=CC(=C4NC3=N2)NC)F)N5C[C@@]6([H])[C@@H]([C@@]6(C)C5)N.[H][H]
InChI: InChI=1S/C22H23FN8O.H2/c1-10-26-6-12(7-27-10)32-21-29-19-16(13-4-11(23)5-15(25-3)17(13)28-19)20(30-21)31-8-14-18(24)22(14,2)9-31;/h4-7,14,18,25H,8-9,24H2,1-3H3,(H,28,29,30);1H/t14-,18-,22-;/m0./s1
External links:
Citation: https://academic.oup.com/jac/article-abstract/75/10/2835/5878045?redirectedFrom=fulltext

AntibioticDB is supported by GARDP.

If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.