Metronidazole (Flagyl)

Class: Nitroimidazole

Spectrum of activity:	Gram-positive
Details of activity:	Effective against C. difficile and Fusobacterium infections. Only effective against anaerobic bacteria.
Institute where first reported:	Pfizer, USA
Year first mentioned:	1960
Highest developmental phase:	Approved by FDA in 1995
Development status:	Approved
Reason Dropped:	Other formulations were discontinued

Chemical structure(s):
Canonical SMILES:	CC1=NC=C(N1CCO)[N+](=O)[O-]
Isomeric SMILES:	CC1=NC=C(N1CCO)[N+](=O)[O-]
InChI:	InChI=1S/C6H9N3O3/c1-5-7-4-6(9(11)12)8(5)2-3-10/h4,10H,2-3H2,1H3
InChI Key:	VAOCPAMSLUNLGC-UHFFFAOYSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/4173

External links:
Guide to Pharmacology:	metronidazole
Main Source:	https://academic.oup.com/cid/article/50/Supplement_1/S16/365006
Citation:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC89320/