Compound ID | 1541

Update compound information

CPZEN-45 analog 1

Class: Mycolyl arabinogalactan biosynthesis inhibitor

Details of activity: Novel antituberculosis drug. Also active against M. avium, M intracellulare and M bovis
Institute where first reported: Institute of Microbial Chemistry, Kamiosaki, Shinagawa-ku, Tokyo, Japan
Year first mentioned: 2019
Highest developmental phase: Preclinical
Chemical structure(s):
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Molecular weight: 660.67
Iso. SMILES: NC[C@@H]1[C@@H](O)[C@@H](O)[C@H](O[C@H]([C@@H]2[C@H](O)[C@H](O)[C@H](N3C(NC(C=C3)=O)=O)O2)[C@H]4C(N(C)C(C(NC5=CC=C(CC)C=C5)=O)=CCN4C)=O)O1
InChI Key: SJVUDZYDONZYBG-DRYUJPJPSA-N
Can. SMILES: CCC1=CC=C(C=C1)NC(=O)C2=CCN(C)[C@@H]([C@@H]([C@@H]3[C@@H]([C@@H]([C@H](N4C=CC(=O)NC4=O)O3)O)O)O[C@H]5[C@@H]([C@@H]([C@@H](CN)O5)O)O)C(=O)N2C
InChI: InChI=1S/C30H40N6O11/c1-4-14-5-7-15(8-6-14)32-26(42)16-9-11-34(2)19(27(43)35(16)3)24(47-29-23(41)20(38)17(13-31)45-29)25-21(39)22(40)28(46-25)36-12-10-18(37)33-30(36)44/h5-10,12,17,19-25,28-29,38-41H,4,11,13,31H2,1-3H3,(H,32,42)(H,33,37,44)/t17-,19+,20-,21-,22+,23-,24+,25+,28-,29+/m1/s1
External links:
Citation: https://www.nature.com/articles/s41429-019-0225-5

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