Compound ID | 155

Update compound information

Amixicile

Class: Antibiofilm agent (nitazoxanide derivative)

Spectrum of activity: Gram-positive
Details of activity: Clostridium difficile infections (CDI)
Propensity to select resistant mutants: Yes
Institute where first reported: Department of Medicine, Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, USA
Year first mentioned: 2012
Highest developmental phase: Preclinical
Development status: Active
Chemical structure(s):
Click here for structure editor
Molecular weight: 342.8
Iso. SMILES: C1=CC=C(C(=C1)CCCN)C(=O)NC2=NC=C(S2)[N+](=O)[O-].Cl
InChI Key: NJLRBHXFDYMOLR-UHFFFAOYSA-N
Can. SMILES: C1=CC(=C(C=C1)C(=O)NC2=NC=C([N+](=O)[O-])S2)CCCN.Cl
InChI: InChI=1S/C13H14N4O3S.ClH/c14-7-3-5-9-4-1-2-6-10(9)12(18)16-13-15-8-11(21-13)17(19)20;/h1-2,4,6,8H,3,5,7,14H2,(H,15,16,18);1H
External links:
Structure link: https://pubchem.ncbi.nlm.nih.gov/compound/46916955
Citations:
  • http://aac.asm.org/content/58/8/4703.short
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3421617/
  • https://journals.asm.org/doi/10.1128/aac.00360-12

    • AntibioticDB is supported by GARDP.

    If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

    The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.