Compound ID | 1550

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2-(pyrazol-1-yl)- thiazole Compound 5

Class: Protein synthesis inhibitor

Spectrum of activity: Gram-negative
Details of activity: Antimicrobial activity against E.coli
Institute where first reported: Institute of Biochemistry and Genetics Russian Academy of Science, Russia
Year first mentioned: 2019
Highest developmental phase: Preclinical
Chemical structure(s):
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Molecular weight: 404.92
Iso. SMILES: ClC1=CC=C(CC2=C(O)N(C3=NC(C)=C(C(NCCC)=O)S3)N=C2C)C=C1
InChI Key: ZWSMXYMALRCSCH-UHFFFAOYSA-N
Can. SMILES: CCCNC(=O)C1=C(C)N=C(N2C(=C(CC3=CC=C(C=C3)Cl)C(=N2)C)O)S1
InChI: InChI=1S/C19H21ClN4O2S/c1-4-9-21-17(25)16-12(3)22-19(27-16)24-18(26)15(11(2)23-24)10-13-5-7-14(20)8-6-13/h5-8,26H,4,9-10H2,1-3H3,(H,21,25)
External links:
Citation: https://www.nature.com/articles/s41429-019-0211-y

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