Compound ID | 1551

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2-(pyrazol-1-yl)- thiazole Compound 6

Class: Protein synthesis inhibitor

Spectrum of activity: Gram-negative
Details of activity: Antimicrobial activity against E.coli
Institute where first reported: Institute of Biochemistry and Genetics Russian Academy of Science, Russia
Year first mentioned: 2019
Highest developmental phase: Preclinical
Chemical structure(s):
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Molecular weight: 417.3
Iso. SMILES: BrC1=CC=C(NC(CCC2=C(O)N(C3=NC(C)=C(C)C3)N=C2C)=O)C=C1
InChI Key: MHNINKPTHDFGGG-UHFFFAOYSA-N
Can. SMILES: CC1=C(C)N=C(C1)N2C(=C(CCC(=O)NC3=CC=C(C=C3)Br)C(=N2)C)O
InChI: InChI=1S/C19H21BrN4O2/c1-11-10-17(21-12(11)2)24-19(26)16(13(3)23-24)8-9-18(25)22-15-6-4-14(20)5-7-15/h4-7,26H,8-10H2,1-3H3,(H,22,25)
External links:
Citation: https://www.nature.com/articles/s41429-019-0211-y

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