Compound ID | 1569

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NPS-2143

Class: Small molecule antibacterial agent

Agent Type: Synthetic; Small molecule; Indirect acting;
Spectrum of activity: Gram-positive
Mechanism of action: CaSR antagonist; regulates host immune response
Year first mentioned: 2001
Development status: Experimental
Chemical structure(s):
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Molecular weight: 408.92
Iso. SMILES: CC(C)(CC1=CC2=CC=CC=C2C=C1)NC[C@H](COC3=C(C(=CC=C3)Cl)C#N)O
InChI Key: PZUJQWHTIRWCID-HXUWFJFHSA-N
Can. SMILES: CC(C)(CC1=CC2=C(C=CC=C2)C=C1)NC[C@H](COC3=C(C#N)C(=CC=C3)Cl)O
InChI: InChI=1S/C24H25ClN2O2/c1-24(2,13-17-10-11-18-6-3-4-7-19(18)12-17)27-15-20(28)16-29-23-9-5-8-22(25)21(23)14-26/h3-12,20,27-28H,13,15-16H2,1-2H3/t20-/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/Nps-2143
Guide to Pharmacology: NPS 2143
Citation: https://www.nature.com/articles/s41429-019-0177-9

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