NPS-2143

Class: CaSR antagonist

Spectrum of activity:	Gram-positive
Year first mentioned:	2001
Highest developmental phase:	Preclinical

Chemical structure(s):
Canonical SMILES:	CC(C)(CC1=CC2=C(C=CC=C2)C=C1)NC[C@H](COC3=C(C#N)C(=CC=C3)Cl)O
Isomeric SMILES:	CC(C)(CC1=CC2=CC=CC=C2C=C1)NC[C@H](COC3=C(C(=CC=C3)Cl)C#N)O
InChI:	InChI=1S/C24H25ClN2O2/c1-24(2,13-17-10-11-18-6-3-4-7-19(18)12-17)27-15-20(28)16-29-23-9-5-8-22(25)21(23)14-26/h3-12,20,27-28H,13,15-16H2,1-2H3/t20-/m1/s1
InChI Key:	PZUJQWHTIRWCID-HXUWFJFHSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/Nps-2143

External links:
Guide to Pharmacology:	NPS 2143
Main Source:	https://www.nature.com/articles/s41429-019-0177-9