Compound ID | 157

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Ozenoxacin

Class: Quinolone

Spectrum of activity: Gram-positive
Details of activity: Acute bacterial skin and skin structure infections
Description: Preclinical In Vitro and In Vivo Absorption Evaluation Of Ozenoxacin (GF-001001-00): A Novel Topical Non-Fluorinated Quinolone. By: Santos, B.; Albet, C.; Orriols, A.; et al.
Institute where first reported: Ferrer Pharma, Spain
Year first mentioned: 2007
Highest developmental phase: Approved by FDA in 2017
Development status: Approved
Chemical structure(s):
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Molecular weight: 363.41
Iso. SMILES: CC1=CC(=CN=C1NC)C2=C(C3=C(C=C2)C(=O)C(=CN3C4CC4)C(=O)O)C
InChI Key: XPIJWUTXQAGSLK-UHFFFAOYSA-N
Can. SMILES: CC1=CC(=CN=C1NC)C2=CC=C3C(=C2C)N(C=C(C3=O)C(=O)O)C4CC4
InChI: InChI=1S/C21H21N3O3/c1-11-8-13(9-23-20(11)22-3)15-6-7-16-18(12(15)2)24(14-4-5-14)10-17(19(16)25)21(26)27/h6-10,14H,4-5H2,1-3H3,(H,22,23)(H,26,27)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/9863827
Guide to Pharmacology: ozenoxacin
Citations:
  • http://aac.asm.org/content/57/12/6389.full
  • http://productos.ferrer.com/innovation/key-development-projects

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