Compound ID | 1591
NPS-2143 derivative 43
Class: Small molecule antibacterial agent
| Agent Type: | Synthetic; Small molecule; Indirect acting; |
| Spectrum of activity: | Gram-positive |
| Mechanism of action: | CaSR antagonist; regulates host immune response |
| Target Pathogen: | Active against methicillin-resistant and -susceptible Staphylococcus aureus |
| Institute where first reported: | Department of Medicinal Chemistry, Chengdu, China |
| Year first mentioned: | 2019 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://www.nature.com/articles/s41429-019-0177-9 |
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