Compound ID | 1615

Update compound information

2-thio-5-(tert-butyl)-6-azauracil

Class: Nucleoside analogue

Agent Type: Synthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-positive, Gram-negative & Antimycobacterial
Mechanism of action: Flavin-dependent thymidylate synthase inhibitor; ThyX inhibitor
Target Pathogen: Active against Staphylococcus aureus, Mycobacterium smegmatis, Escherichia coli, and Pseudomonas aeruginosa
Institute where first reported: Russian Academy of Sciences, Moscow, Russia
Year first mentioned: 2019
Development status: Experimental
Chemical structure(s):
Click here for structure editor
Molecular weight: 185.25
Iso. SMILES: O=C1C(C(C)(C)C)=NNC(N1)=S
InChI Key: IULZTDKMPBUWDF-UHFFFAOYSA-N
Can. SMILES: CC(C)(C)C1=NNC(=S)NC1=O
InChI: InChI=1S/C7H11N3OS/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12)
External links:
Citation: https://www.nature.com/articles/s41429-019-0158-z

AntibioticDB is supported by GARDP.

If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.