Compound ID | 1620

Update compound information

2’-Deoxy-5-(tert-butyl)-6-azauridine

Class: Nucleoside analog

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Compound shows activity against B. subtilis, L. mesenteroides, S. aureus, M. smegmatis, E.coli and P. aeruginosa
Institute where first reported: Russian Academy of Sciences, Moscow, Russia
Year first mentioned: 2019
Highest developmental phase: Preclinical
Chemical structure(s):
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Molecular weight: 285.3
Iso. SMILES: O[C@@H]1[C@@H](CO)O[C@@H](N2C(NC(C(C(C)(C)C)=N2)=O)=O)C1
InChI Key: OUVZOJKUHOZIGY-XLPZGREQSA-N
Can. SMILES: CC(C)(C)C1=NN([C@H]2C[C@@H]([C@@H](CO)O2)O)C(=O)NC1=O
InChI: InChI=1S/C12H19N3O5/c1-12(2,3)9-10(18)13-11(19)15(14-9)8-4-6(17)7(5-16)20-8/h6-8,16-17H,4-5H2,1-3H3,(H,13,18,19)/t6-,7+,8+/m0/s1
External links:
Citation: https://www.nature.com/articles/s41429-019-0158-z

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