Compound ID | 1631

Update compound information

Synthesized Azolylthioacetamide 1

Class: Beta-lactamase inhibitor

Spectrum of activity: Gram-negative
Details of activity: Activity demonstrated against E.coli expressing NDM-1
Institute where first reported: Northwest University, Xi'an, China
Year first mentioned: 2019
Highest developmental phase: Preclinical
Chemical structure(s):
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Molecular weight: 358.4
Iso. SMILES: O=C(SC1=NN=C(C2=CC([N+]([O-])=O)=CC=C2)S1)NC3=CC=CC=C3
InChI Key: KJFJQVPEVLJJGW-UHFFFAOYSA-N
Can. SMILES: C1=CC=C(C=C1)NC(=O)SC2=NN=C(C3=CC(=CC=C3)[N+](=O)[O-])S2
InChI: InChI=1S/C15H10N4O3S2/c20-14(16-11-6-2-1-3-7-11)24-15-18-17-13(23-15)10-5-4-8-12(9-10)19(21)22/h1-9H,(H,16,20)
External links:
Citation: https://www.nature.com/articles/s41429-018-0121-4

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