Compound ID | 1643

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Synthesized Azolylthioacetamide 13

Class: Beta-lactamase inhibitor

Spectrum of activity: Gram-negative
Details of activity: Activity demonstrated against E.coli expressing NDM-1
Institute where first reported: Northwest University, Xi'an, China
Year first mentioned: 2019
Highest developmental phase: Preclinical
Chemical structure(s):
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Molecular weight: 528.7
Iso. SMILES: O=C(CSC1=NN=C(CCC2=NN=C(SCC(NC3=CC=CC=C3)=O)S2)S1)NC4=CC=CC=C4
InChI Key: RLRWNGHBLDXFSA-UHFFFAOYSA-N
Can. SMILES: C1=CC=C(C=C1)NC(=O)CSC2=NN=C(CCC3=NN=C(SCC(=O)NC4=CC=CC=C4)S3)S2
InChI: InChI=1S/C22H20N6O2S4/c29-17(23-15-7-3-1-4-8-15)13-31-21-27-25-19(33-21)11-12-20-26-28-22(34-20)32-14-18(30)24-16-9-5-2-6-10-16/h1-10H,11-14H2,(H,23,29)(H,24,30)
External links:
Citation: https://www.nature.com/articles/s41429-018-0121-4

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