Compound ID | 171

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MBX 1641

Class: Antivirulence agent (T3SS inhibitor)

Spectrum of activity: Gram-negative
Details of activity: Phenoxyacetamide inhibitor of Pseudomonas aeruginosa type III secretion system
Institute where first reported: Microbiotix Inc, USA
Year first mentioned: 2014
Highest developmental phase: Preclinical
Development status: Active
Chemical structure(s):
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Molecular weight: 368.21
Iso. SMILES: CC(C(=O)NCC1=CC2=C(C=C1)OCO2)OC3=C(C=C(C=C3)Cl)Cl
InChI Key: HTLITQCTVJDOQP-UHFFFAOYSA-N
Can. SMILES: CC(C(=O)NCC1=CC=C2C(=C1)OCO2)OC3=CC=C(C=C3Cl)Cl
InChI: InChI=1S/C17H15Cl2NO4/c1-10(24-14-5-3-12(18)7-13(14)19)17(21)20-8-11-2-4-15-16(6-11)23-9-22-15/h2-7,10H,8-9H2,1H3,(H,20,21)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/2862146
Citations:
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2863679/pdf/1598-09.pdf
  • http://www.ncbi.nlm.nih.gov/pubmed/?term=PMC4023729
  • https://www.microbiotix.com/programs/

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