Compound ID | 1737

Bezlotoxumab, Zinplava

Class: Antibody

Agent Type: Natural product; Direct acting; Antibody;
Spectrum of activity: Gram-positive
Mechanism of action: Neutralizes toxins produced by Clostridioides difficile
Target Pathogen: Active against Clostridioides difficile
Institute where first reported: Medarex Inc and MassBiologics; Merck Sharp & Dohme
Year first mentioned: 2009
Highest development stage: Approved by FDA in 2016
Development status: Approved
External links:
Guide to Pharmacology: bezlotoxumab
Citation: https://www.nature.com/articles/s41429-020-0344-z

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