Compound ID | 1777

Update compound information

POL7306

Class: Antimicrobial peptidomimetic (outer-membrane protein targeting antibiotic)

Spectrum of activity: Gram-negative
Details of activity: Active against Enterobacteriaceae and non-fermenters; targets outer-membrane proteins
Description: Synthetic compound; cyclic peptide-like molecules that mimic secondary structures of proteins.
Institute where first reported: Polyphor (now Spexis)
Year first mentioned: 2018
Highest developmental phase: Preclinical
Development status: Inactive (as of 2022)
External links:
Citations:
  • https://pubmed.ncbi.nlm.nih.gov/32087024/
  • https://spexisbio.com/wp-content/uploads/2019/12/Nature-article_OMPTA_Oct19.pdf
  • https://www.polyphor.com
  • https://academic.oup.com/jac/article/75/6/1518/5748154?login=true#203547101

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