Compound ID | 1778
TMR010
Synonym(s): EBL-1463 | EBL1463 | EBL 1463 | TMR-010 | TMR 010
Class: Small molecule antibacterial agent
| Spectrum of activity: | Gram-negative |
| Mechanism of action: | Cell wall synthesis inhibitor. Penicillin-Binding Protein (PBP) inhibitor; reported through personal communication as stable to class A, B, C, and D beta-lactamases |
| Target Pathogen: | Active against Enterobacteriaceae |
| Description: | Synthetic compound (dabocin; diazabicyclooctane scaffold); non-beta-lactam inhibitor of PBPs |
| Institute where first reported: | Mutabilis; Tamrisa |
| Year first mentioned: | 2017 |
| Highest developmental phase: | Preclinical |
| Development status: | Active |
| External links: | |
| Citations: |
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