Compound ID | 1778

TMR010

Synonym(s): EBL-1463  |  EBL1463  |  EBL 1463  |  TMR-010  |  TMR 010

Class: Small molecule antibacterial agent

Agent Type: Synthetic; Direct acting;
Spectrum of activity: Gram-negative
Mechanism of action: Cell wall synthesis inhibitor. Penicillin binding protein inhibitor; PBP inhibitor
Target Pathogen: Active against carbapenem-resistant Enterobacterales
Description: Synthetic compound (dabocin; diazabicyclooctane scaffold); non-beta-lactam inhibitor of PBPs
Institute where first reported: Mutabilis; Tamrisa
Year first mentioned: 2017
Highest development stage: Preclinical
Development status: Experimental

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