Compound ID | 1785
MET-X
Class: Beta-lactamase inhibitor (metallo beta-lactamase inhibitor)
| Spectrum of activity: | Gram-negative |
| Details of activity: | Inhibits metallo-β-lactamases which hydrolyse carbapenems, especially in E. coli and K. pneumoniae. Only for use in combination with a carbapenem |
| Description: | Producing metallo-β-lactamase is just one reason for resistance to carbapenems. These enzymes are still uncommon in most high-income countries. |
| Institute where first reported: | Infex Therapeutics (formerly AMR Center), Medivir |
| Year first mentioned: | 2022 |
| Development status: | Active (as of 2022) |
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