Compound ID | 1787
PED-011
Class: Small molecule antibacterial agent
| Agent Type: | Synthetic; Direct acting; |
| Spectrum of activity: | Gram-negative |
| Mechanism of action: | Fatty acid synthesis inhibitor. Inhibits the fatty acid pathway by silencing the AcpP gene; AcpP inhibitor |
| Target Pathogen: | Active against Escherichia coli |
| Description: | Synthetic compound; the challenge of uptake and internalisation of an antisense oligonucleotide is addressed by a new porin translocation technology.; an antisense oligonucleotide |
| Institute where first reported: | Pedanius Therapeutics |
| Year first mentioned: | 2019 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://pedaniustherapeutics.com/pipeline |
| Patent: | WO2020109792A1 |
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