Compound ID | 1809
G2824
Class: Lgt inhibitor
| Spectrum of activity: | Gram-negative |
| Details of activity: | Inhibits lipoprotein diacylglyceryl transferase (Lgt) that catalyzes the first step in the biogenesis of Gram-negative bacterial lipoproteins. Active against Gram-negative bacteria. |
| Description: | Synthetic macrocyclic peptide |
| Institute where first reported: | Genentech |
| Year first mentioned: | 2021 |
| Highest developmental phase: | Preclinical |
| Development status: | Active (as of 2022) |
| External links: | |
| Citation: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316002/ |
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