Compound ID | 1817

Update compound information

MAC13772

Class: Biotin biosynthesis inhibitor

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Inhibits BioA, the antepenultimate step in biotin biosynthesis
Year first mentioned: 2013
Highest developmental phase: Preclinical
Development status: Inactive (as of 2022)
Chemical structure(s):
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Molecular weight: 227.24
Iso. SMILES: C1=CC=C(C(=C1)[N+](=O)[O-])SCC(=O)NN
InChI Key: CZXFCCXLFQCYBK-UHFFFAOYSA-N
Can. SMILES: C1=CC(=C(C=C1)SCC(=O)NN)[N+](=O)[O-]
InChI: InChI=1S/C8H9N3O3S/c9-10-8(12)5-15-7-4-2-1-3-6(7)11(13)14/h1-4H,5,9H2,(H,10,12)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/2807216
Citations:
  • https://www.nature.com/articles/s41564-019-0595-2
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970981/

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