ANT3310

Class: Beta-lactamase inhibitor (diazabicyclooctane [DBO])

Details of activity:	Inhibits class A and C β-lactamases; for use in combination with meropenem
Combined with other compounds:	Yes
Description:	Synthetic compound. Inhibitor of serine beta-lactamases
Institute where first reported:	Antabio
Year first mentioned:	2020
Highest developmental phase:	Preclinical
Development status:	Active (as of 2022)

Chemical structure(s):
Canonical SMILES:	C1C[C@@H](F)N2C[C@@H]1N(C2=O)OS(=O)(=O)[O-].[Na+]
Isomeric SMILES:	C1C[C@H](N2C[C@@H]1N(C2=O)OS(=O)(=O)[O-])F.[Na+]
InChI:	InChI=1S/C6H9FN2O5S.Na/c7-5-2-1-4-3-8(5)6(10)9(4)14-15(11,12)13;/h4-5H,1-3H2,(H,11,12,13);/q;+1/p-1/t4-,5+;/m1./s1
InChI Key:	UIJIKXQAJBMNIR-JBUOLDKXSA-M
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/153516440

External links:
Guide to Pharmacology:	ANT3310
Main Source:	https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c01535