Compound ID | 1828

GSK3882347

Class: FimH antagonist

Spectrum of activity: Gram-negative
Details of activity: Mannose-containing small molecule drug, that targets the adhesive protein in bacteria FimH and prevents adhesion of E. coli to the bladder epithelial cells
Description: Synthetic compound
Institute where first reported: GSK, Fimbrion Therapeutics
Year first mentioned: 2020
Highest developmental phase: Phase 1
Development status: Active (as of 2022)

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