Bekanamycin

Synonym(s): kanamycin B  |  nebramycin V

Class: Aminoglycoside

Spectrum of activity:	Gram-positive  &  Gram-negative
Details of activity:	Inhibits protein synthesis by binding to the 30S subunit of the bacterial ribosome. Active against Gram-positive and Gram-negative bacteria
Description:	Streptomyces natural product. Used for topical application
Year first mentioned:	1969
Development status:	Approved, off-patent

Chemical structure(s):
Canonical SMILES:	C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)N)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@@H](CN)O3)O)O)N)N
Isomeric SMILES:	C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)N)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)N)N
InChI:	InChI=1S/C18H37N5O10/c19-2-6-11(26)12(27)9(23)17(30-6)32-15-4(20)1-5(21)16(14(15)29)33-18-13(28)8(22)10(25)7(3-24)31-18/h4-18,24-29H,1-3,19-23H2/t4-,5+,6+,7+,8-,9+,10+,11+,12+,13+,14-,15+,16-,17+,18+/m0/s1
InChI Key:	SKKLOUVUUNMCJE-FQSMHNGLSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/439318

External links:
Guide to Pharmacology:	bekanamycin
Main Source:	https://pubmed.ncbi.nlm.nih.gov/1150536/
Citation:	https://pubmed.ncbi.nlm.nih.gov/3089002/