Compound ID | 189
Dextrin-colistin polymer conjugate
Class: Antimicrobial peptide
| Agent Type: | Natural product; Direct acting; |
| Spectrum of activity: | Gram-negative |
| Mechanism of action: | Membrane-active agent. Allows targeted delivery of colistin |
| Target Pathogen: | Active against Acinetobacter baumannii |
| Combined with other compounds: | Yes |
| Description: | A polymer conjugated with polymyxin; conjugation apparently reduces colistin's toxicity |
| Institute where first reported: | Advanced Therapies Group, School of Dentistry, Cardiff University, Heath Park, Cardiff, United Kingdom |
| Year first mentioned: | 2014 |
| Development status: | Experimental |
| External links: | |
| Citations: |
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