Compound ID | 1897
Class: Beta-lactam (cephalosporin, second generation)
Spectrum of activity: | Gram-positive & Gram-negative |
Details of activity: | Binds to bacterial penicillin-binding proteins (PBP) and interferes with bacterial cell wall integrity and synthesis. Active against Gram-positive bacteria and against many Enterobacteriaceae but vulnerable to extended-spectum beta-lactamases (ESBL) |
Description: | Semisynthetic Cephalosporin, derived from Cephalosporin C. Oral and iv application |
Year first mentioned: | 1971 |
Development status: | Approved, off-patent |
Chemical structure(s): | |||||||||||
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External links: | |
PubChem link: | https://pubchem.ncbi.nlm.nih.gov/compound/5361202 |
Guide to Pharmacology: | cefuroxime |
Citation: | https://pubmed.ncbi.nlm.nih.gov/32959896/ |