Compound ID | 1923
Synonym(s): Benzylpenicillin
Class: Beta-lactam (penicillin)
Spectrum of activity: | Gram-positive |
Details of activity: | Binds to bacterial penicillin-binding proteins (PBP) and interferes with bacterial cell wall integrity and synthesis. Active against Gram-positive bacteria, but vulnerable to penicillinases produced by staphylococci |
Description: | Natural compound. Parenteral application |
Year first mentioned: | 1938 |
Highest developmental phase: | Approved by FDA in 1951 |
Development status: | Approved |
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