Cadazolid

Class: Quinolonyl-oxazolidinone

Spectrum of activity:	Gram-positive
Details of activity:	C. difficile-associated diarrhea
Institute where first reported:	Actelion Pharmaceuticals, Switzerland
Year first mentioned:	2012
Highest developmental phase:	Phase 3
Development status:	Active

Chemical structure(s):
Canonical SMILES:	C1CC1N2C=C(C(=O)C3=C2C=C(C(=C3)F)N4CCC(CC4)(COC5=CC=C(C=C5F)N6C[C@H](CO)OC6=O)O)C(=O)O
Isomeric SMILES:	C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCC(CC4)(COC5=C(C=C(C=C5)N6C[C@@H](OC6=O)CO)F)O)F)C(=O)O
InChI:	InChI=1S/C29H29F2N3O8/c30-21-10-19-23(33(16-1-2-16)13-20(26(19)36)27(37)38)11-24(21)32-7-5-29(40,6-8-32)15-41-25-4-3-17(9-22(25)31)34-12-18(14-35)42-28(34)39/h3-4,9-11,13,16,18,35,40H,1-2,5-8,12,14-15H2,(H,37,38)/t18-/m1/s1
InChI Key:	XWFCFMXQTBGXQW-GOSISDBHSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/44242317

External links:
Guide to Pharmacology:	cadazolid
Citations:	http://aac.asm.org/content/58/2/901.full\ https://www1.actelion.com/en-rebranded/investors/news-archive.page?newsId=2111437 https://www.escmid.org/escmid_publications/escmid_elibrary/?q=Cadazolid&id=2173&L=0&x=0&y=0