Brodimoprim

Class: Diaminopyrimidine

Spectrum of activity:	Gram-positive
Details of activity:	Inhibits dihydrofolic acid reductase and thus, the synthesis of purine
Description:	Synthetic compound. Trimethoprim derivative
Year first mentioned:	1984
Development status:	Inactive

Chemical structure(s):
Canonical SMILES:	COC1=CC(=CC(=C1Br)OC)CC2=C(N)N=C(N)N=C2
Isomeric SMILES:	COC1=CC(=CC(=C1Br)OC)CC2=CN=C(N=C2N)N
InChI:	InChI=1S/C13H15BrN4O2/c1-19-9-4-7(5-10(20-2)11(9)14)3-8-6-17-13(16)18-12(8)15/h4-6H,3H2,1-2H3,(H4,15,16,17,18)
InChI Key:	BFCRRLMMHNLSCP-UHFFFAOYSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/68760

External links:
Guide to Pharmacology:	brodimoprim
Main Source:	https://www.karger.com/Article/Abstract/238239
Citations:	https://pubmed.ncbi.nlm.nih.gov/7562018/ https://pubmed.ncbi.nlm.nih.gov/8195838/