Compound ID | 1970
Synonym(s): Fumigacin
Class: Fusidane
Spectrum of activity: | Gram-positive |
Details of activity: | Inhibits the function of elongation factor G (EF-G), leading to the inhibition of protein synthesis. Bacteriostatic activity against Gram-positive bacteria |
Description: | Natural product produced by Aspergillus and other fungi |
Year first mentioned: | 1943 |
Development status: | Experimental |
Chemical structure(s): | |
Canonical SMILES: | CC(=CCCC(=C1[C@@H]2CC[C@H]3[C@@]4(C)C=CC(=O)[C@@H](C)[C@@H]4[C@@H](C(=O)[C@]3(C)[C@@]2(C)C[C@@H]1OC(=O)C)OC(=O)C)C(=O)O)C |
Isomeric SMILES: | C[C@H]1[C@@H]2[C@@H](C(=O)[C@]3([C@H]([C@]2(C=CC1=O)C)CC[C@@H]4[C@@]3(C[C@@H](C4=C(CCC=C(C)C)C(=O)O)OC(=O)C)C)C)OC(=O)C |
InChI: | InChI=1S/C33H44O8/c1-17(2)10-9-11-21(30(38)39)26-22-12-13-25-31(6)15-14-23(36)18(3)27(31)28(41-20(5)35)29(37)33(25,8)32(22,7)16-24(26)40-19(4)34/h10,14-15,18,22,24-25,27-28H,9,11-13,16H2,1-8H3,(H,38,39)/t18-,22+,24+,25+,27-,28+,31-,32+,33-/m1/s1 |
InChI Key: | MDFZYGLOIJNNRM-HYNRAYKSSA-N |
Structure link: | https://pubchem.ncbi.nlm.nih.gov/compound/Helvolic-acid |