Compound ID | 1976

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Tinidazole

Class: Nitroimidazole

Agent Type: Natural product; Small molecule; Direct acting;
Mechanism of action: Reduced in vivo to give radical species that are toxic to cells
Description: Isomer of a natural producht azomycin produced by streptomyces. Mainly used for protozoal infections and Gram-negative anaerobe bacteria
Year first mentioned: 1969
Highest development stage: Approved
Development status: Approved
Chemical structure(s):
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Molecular weight: 247.27
Iso. SMILES: CCS(=O)(=O)CCN1C(=NC=C1[N+](=O)[O-])C
InChI Key: HJLSLZFTEKNLFI-UHFFFAOYSA-N
Can. SMILES: CCS(=O)(=O)CCN1C(=NC=C1[N+](=O)[O-])C
InChI: InChI=1S/C8H13N3O4S/c1-3-16(14,15)5-4-10-7(2)9-6-8(10)11(12)13/h6H,3-5H2,1-2H3
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/5479
Guide to Pharmacology: tinidazole
Citations:
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893931/
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430554/
  • https://academic.oup.com/jac/article-abstract/31/1/9/800661?redirectedFrom=fulltext&login=false

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