Compound ID | 1976

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Tinidazole

Class: Nitroimidazole

Details of activity: Nitroimidazoles are prodrugs which are reduced in vivo to give radical species that are toxic to cells. The exact details of its mode of action remain unclear and may vary among species.
Description: Isomer of a natural producht azomycin produced by streptomyces. Mainly used for protozoal infections and Gram-negative anaerobe bacteria
Year first mentioned: 1969
Development status: Approved, off-patent
Chemical structure(s):
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Molecular weight: 247.27
Iso. SMILES: CCS(=O)(=O)CCN1C(=NC=C1[N+](=O)[O-])C
InChI Key: HJLSLZFTEKNLFI-UHFFFAOYSA-N
Can. SMILES: CCS(=O)(=O)CCN1C(=NC=C1[N+](=O)[O-])C
InChI: InChI=1S/C8H13N3O4S/c1-3-16(14,15)5-4-10-7(2)9-6-8(10)11(12)13/h6H,3-5H2,1-2H3
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/5479
Guide to Pharmacology: tinidazole
Citations:
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893931/
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430554/
  • https://academic.oup.com/jac/article-abstract/31/1/9/800661?redirectedFrom=fulltext&login=false

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