Furazolidone

Class: Nitrofuran

Details of activity:	Inhibits monoamine oxidase activity. Active against many Enterobacteriaceae (Salmonella, shigella) and Helicobacter pylori.
Combined with other compounds:	Yes
Description:	Synthetic compound. Oral application for eradication of Helicobacter pylori. Used in veterinary medicine
Year first mentioned:	1953
Development status:	Approved, off-patent

Chemical structure(s):
Canonical SMILES:	C1=C(C=NN2CCOC2=O)OC(=C1)[N+](=O)[O-]
Isomeric SMILES:	C1COC(=O)N1N=CC2=CC=C(O2)[N+](=O)[O-]
InChI:	InChI=1S/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2
InChI Key:	PLHJDBGFXBMTGZ-UHFFFAOYSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/3435

External links:
Guide to Pharmacology:	furazolidone
Main Source:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145784/
Citations:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993017/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486336/