Compound ID | 1979

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Furazolidone

Class: Nitrofuran

Agent Type: Synthetic; Small molecule; Direct acting;
Mechanism of action: Inhibits monoamine oxidase activity
Target Pathogen: Active against many Enterobacteriaceae (Salmonella, Shigella), and Helicobacter pylori
Combined with other compounds: Yes
Description: Synthetic compound. Oral application for eradication of Helicobacter pylori. Used in veterinary medicine
Year first mentioned: 1953
Highest development stage: Approved
Development status: Approved
Chemical structure(s):
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Molecular weight: 225.16
Iso. SMILES: C1COC(=O)N1N=CC2=CC=C(O2)[N+](=O)[O-]
InChI Key: PLHJDBGFXBMTGZ-UHFFFAOYSA-N
Can. SMILES: C1=C(C=NN2CCOC2=O)OC(=C1)[N+](=O)[O-]
InChI: InChI=1S/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/3435
Guide to Pharmacology: furazolidone
Citations:
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993017/
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486336/
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145784/

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