Compound ID | 1985

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Nifurzide

Class: Nitrofuran

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Broad mechanism of action by by damaging bacterial DNA. Active against protozoal species.
Description: Synthetic compound. Mainly used in veterinary medicine for bacterial gastrointestinal infection.
Year first mentioned: 1981
Development status: Approved, off-patent
Chemical structure(s):
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Molecular weight: 336.28
Iso. SMILES: C1=C(OC(=C1)[N+](=O)[O-])/C=C/C=N/NC(=O)C2=CC=C(S2)[N+](=O)[O-]
InChI Key: IDUMOVRJNBNOTR-BIZLIJPVSA-N
Can. SMILES: C(=C\C1=CC=C([N+](=O)[O-])O1)/C=N/NC(=O)C2=CC=C([N+](=O)[O-])S2
InChI: InChI=1S/C12H8N4O6S/c17-12(9-4-6-11(23-9)16(20)21)14-13-7-1-2-8-3-5-10(22-8)15(18)19/h1-7H,(H,14,17)/b2-1+,13-7+
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/9571044
Guide to Pharmacology: nifurzide
Citations:
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC181457/
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC431119/
  • https://pubmed.ncbi.nlm.nih.gov/4030525/

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