Nifurzide

Class: Nitrofuran

Spectrum of activity:	Gram-positive  &  Gram-negative
Details of activity:	Broad mechanism of action by by damaging bacterial DNA. Active against protozoal species.
Description:	Synthetic compound. Mainly used in veterinary medicine for bacterial gastrointestinal infection.
Year first mentioned:	1981
Development status:	Approved, off-patent

Chemical structure(s):
Canonical SMILES:	C(=C\C1=CC=C([N+](=O)[O-])O1)/C=N/NC(=O)C2=CC=C([N+](=O)[O-])S2
Isomeric SMILES:	C1=C(OC(=C1)[N+](=O)[O-])/C=C/C=N/NC(=O)C2=CC=C(S2)[N+](=O)[O-]
InChI:	InChI=1S/C12H8N4O6S/c17-12(9-4-6-11(23-9)16(20)21)14-13-7-1-2-8-3-5-10(22-8)15(18)19/h1-7H,(H,14,17)/b2-1+,13-7+
InChI Key:	IDUMOVRJNBNOTR-BIZLIJPVSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/9571044

External links:
Guide to Pharmacology:	nifurzide
Main Source:	https://pubmed.ncbi.nlm.nih.gov/4030525/
Citations:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC181457/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC431119/