Nitrofurazone

Synonym(s): nitrofural  |  furacin  |  furacilin

Class: Nitrofuran

Spectrum of activity:	Gram-positive  &  Gram-negative
Details of activity:	Broad mechanism of action by by damaging bacterial DNA. Active against protozoal species.
Description:	Synthetic compound. Carcinogenic and mutagenic. Used for topical application and in veterinary medicine
Year first mentioned:	1946
Development status:	Approved, off-patent, not available in many countries

Chemical structure(s):
Canonical SMILES:	C1=C(/C=N/NC(=O)N)OC(=C1)[N+](=O)[O-]
Isomeric SMILES:	C1=C(OC(=C1)[N+](=O)[O-])/C=N/NC(=O)N
InChI:	InChI=1S/C6H6N4O4/c7-6(11)9-8-3-4-1-2-5(14-4)10(12)13/h1-3H,(H3,7,9,11)/b8-3+
InChI Key:	IAIWVQXQOWNYOU-FPYGCLRLSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/5447130

External links:
Guide to Pharmacology:	nitrofural
Main Source:	https://pubmed.ncbi.nlm.nih.gov/34839952/
Citation:	https://pubmed.ncbi.nlm.nih.gov/36215761/