Furagin

Synonym(s): Furosin  |  furazidin  |  furazidine

Class: Nitrofuran

Spectrum of activity:	Gram-positive  &  Gram-negative
Details of activity:	Broad mechanism of action by by damaging bacterial DNA. Active against protozoal species.
Description:	Synthetic compound. Used for uncomplicated urinary tract infections.
Year first mentioned:	1984
Development status:	Approved, off-patent, not available in many countries

Chemical structure(s):
Canonical SMILES:	C(=C\C1=CC=C([N+](=O)[O-])O1)/C=N/N2CC(=O)NC2=O
Isomeric SMILES:	C1C(=O)NC(=O)N1/N=C/C=C/C2=CC=C(O2)[N+](=O)[O-]
InChI:	InChI=1S/C10H8N4O5/c15-8-6-13(10(16)12-8)11-5-1-2-7-3-4-9(19-7)14(17)18/h1-5H,6H2,(H,12,15,16)/b2-1+,11-5+
InChI Key:	DECBQELQORZLLP-UAIOPKHMSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/6870646

External links:
Guide to Pharmacology:	furagin
Main Source:	https://pubmed.ncbi.nlm.nih.gov/468451/
Citation:	https://pubmed.ncbi.nlm.nih.gov/18060746/