Compound ID | 1987

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Furagin

Synonym(s): Furosin  |  furazidin  |  furazidine

Class: Nitrofuran

Agent Type: Synthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-positive & Gram-negative
Mechanism of action: DNA synthesis inhibitor. Broad mechanism of action by damaging bacterial DNA
Target Pathogen: Active against protozoal species
Description: Synthetic compound. Used for uncomplicated urinary tract infections.
Year first mentioned: 1984
Highest development stage: Approved
Development status: Approved
Chemical structure(s):
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Molecular weight: 264.19
Iso. SMILES: C1C(=O)NC(=O)N1/N=C/C=C/C2=CC=C(O2)[N+](=O)[O-]
InChI Key: DECBQELQORZLLP-UAIOPKHMSA-N
Can. SMILES: C(=C\C1=CC=C([N+](=O)[O-])O1)/C=N/N2CC(=O)NC2=O
InChI: InChI=1S/C10H8N4O5/c15-8-6-13(10(16)12-8)11-5-1-2-7-3-4-9(19-7)14(17)18/h1-5H,6H2,(H,12,15,16)/b2-1+,11-5+
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/6870646
Guide to Pharmacology: furagin
Citations:
  • https://pubmed.ncbi.nlm.nih.gov/18060746/
  • https://pubmed.ncbi.nlm.nih.gov/468451/

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