Compound ID | 20

Dipeptidomimetic Compound 1b

Class: Antimicrobial peptide

Agent Type: Semisynthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-positive
Mechanism of action: Membrane-active agent
Target Pathogen: Active against methicillin-resistant and -susceptible Staphylococcus aureus and Staphylococcus epidermidis
Propensity to select resistant mutants: Yes
Description: Semisynthetic compound designed from the natural product spermidine
Institute where first reported: Peptide Research Laboratory, CSIR-Institute of Genomics and Integrative Biology, Delhi, India
Year first mentioned: 2014
Development status: Experimental

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