Compound ID | 2080

Update compound information

Sulfaperine

Synonym(s): Sulfaperin

Class: Sulfonamide

Agent Type: Synthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-positive & Gram-negative
Mechanism of action: Folate synthesis inhibitor. Sulphonamides are structural analogues of p-aminobenzoic acid and act as competitive inhibitors (and alternate substrates) of dihydropteroate synthase (DHPS) to block the synthesis of folic acid; dihydropteroate synthase inhibitor (DHPS inhibitor)
Description: Synthetic sufanilamide derivative; long-acting (~7 days).
Year first mentioned: 1946
Development status: Experimental
Chemical structure(s):
Click here for structure editor
Molecular weight: 264.31
Iso. SMILES: CC1=CN=C(N=C1)NS(=O)(=O)C2=CC=C(C=C2)N
InChI Key: DZQVFHSCSRACSX-UHFFFAOYSA-N
Can. SMILES: CC1=CN=C(N=C1)NS(=O)(=O)C2=CC=C(C=C2)N
InChI: InChI=1S/C11H12N4O2S/c1-8-6-13-11(14-7-8)15-18(16,17)10-4-2-9(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/68933
Guide to Pharmacology: sulfaperin
Citation: https://pubmed.ncbi.nlm.nih.gov/7447603/

AntibioticDB is supported by GARDP.

If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.