Compound ID | 2119

Nodusmicin

Class: Macrolide (10- and 14-membered macrolactone)

Spectrum of activity: Gram-positive
Details of activity: Activity against Gram-positive bacteria.
Description: Natural product produced by Nocardia; structurally similar to luminamicin and nargenicin
Year first mentioned: 1980
Development status: Experimental
Chemical structure(s):
Canonical SMILES: C[C@@H]1/C=C(/C)\[C@@]23[C@H](C=C[C@@H]4[C@H]3[C@@H]([C@@H](C)[C@H]([C@@H]4O2)O)O)C[C@@H](C(=O)O[C@@H]1[C@@H](C)O)OC
Isomeric SMILES: C[C@@H]1/C=C(\[C@]23[C@@H](C[C@@H](C(=O)O[C@@H]1[C@@H](C)O)OC)C=C[C@@H]4[C@H]2[C@@H]([C@H]([C@H]([C@@H]4O3)O)C)O)/C
InChI: InChI=1S/C23H34O7/c1-10-8-11(2)23-14(9-16(28-5)22(27)29-20(10)13(4)24)6-7-15-17(23)18(25)12(3)19(26)21(15)30-23/h6-8,10,12-21,24-26H,9H2,1-5H3/b11-8-/t10-,12-,13-,14-,15-,16+,17+,18-,19-,20+,21-,23+/m1/s1
InChI Key: LUCYVUUQBYQHOV-GFCOOTNGSA-N
Structure link: https://pubchem.ncbi.nlm.nih.gov/compound/Nodusmicin
External links:
Guide to Pharmacology: nodusmicin
Main Source: https://www.sciencedirect.com/science/article/abs/pii/S0040403900787375
Citation: https://pubs.acs.org/doi/pdf/10.1021/ja00315a053

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