Compound ID | 212

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MAC-0026022

Class: Small molecule antibacterial agent

Agent Type: Synthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-positive
Mechanism of action: Cell wall synthesis inhibitor. Detected by cell wall inhibitor reporter system; shows weak whole cell activity
Description: Synthetic compound from Chembridge and Maybridge Chemicals compound collection
Institute where first reported: Department of Biochemistry and Biomedical Sciences and Michael G. DeGroote Institute of Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada
Year first mentioned: 2014
Development status: Experimental
Chemical structure(s):
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Molecular weight: 380.91
Iso. SMILES: CSC1=C2C(CCCC2=C(S1)C(=O)N/N=C/C3=CC=CC=C3Cl)O
InChI Key: KMJBFEREWIWTAI-DJKKODMXSA-N
Can. SMILES: CSC1=C2C(=C(C(=O)N/N=C/C3=C(C=CC=C3)Cl)S1)CCCC2O
InChI: InChI=1S/C17H17ClN2O2S2/c1-23-17-14-11(6-4-8-13(14)21)15(24-17)16(22)20-19-9-10-5-2-3-7-12(10)18/h2-3,5,7,9,13,21H,4,6,8H2,1H3,(H,20,22)/b19-9+
External links:
Structure link: https://pubchem.ncbi.nlm.nih.gov/compound/9584259
Citations:
  • http://aac.asm.org/content/58/6/3261.full
  • https://journals.asm.org/doi/full/10.1128/aac.02352-14

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