Compound ID | 2127

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Corytuberine

Class: Natural product antibiotic

Agent Type: Natural product; Small molecule; Direct acting;
Spectrum of activity: Gram-negative
Mechanism of action: Fatty acid synthesis inhibitor. Binds to FabD; FabD inhibitor
Target Pathogen: Active agaisnt Helicobacter pylori
Description: Natural product produced by Cissampelos pareira (plant)
Year first mentioned: 2006
Development status: Experimental
Chemical structure(s):
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Molecular weight: 327.38
Iso. SMILES: CN1CCC2=CC(=C(C3=C2[C@@H]1CC4=C3C(=C(C=C4)OC)O)O)OC
InChI Key: WHFUDAOCYRYAKQ-LBPRGKRZSA-N
Can. SMILES: CN1CCC2=C3[C@@H]1CC4=CC=C(C(=C4C3=C(C(=C2)OC)O)O)OC
InChI: InChI=1S/C19H21NO4/c1-20-7-6-11-9-14(24-3)19(22)17-15(11)12(20)8-10-4-5-13(23-2)18(21)16(10)17/h4-5,9,12,21-22H,6-8H2,1-3H3/t12-/m0/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/Corytuberine
Citations:
  • https://www.future-science.com/doi/10.4155/fmc.12.62
  • https://febs.onlinelibrary.wiley.com/doi/full/10.1016/j.febslet.2005.12.085

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