Compound ID | 2128

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CG 3401

Synonym(s): diazaborine

Class: Small molecule antibacterial agent

Spectrum of activity: Gram-negative
Details of activity: Inhibits fatty acid synthesis by binding to FabI. Active against some Gram-negative bacteria and M. tuberculosis
Description: Synthetic boron heterocycle-based compound
Year first mentioned: 1975
Development status: Experimental
Chemical structure(s):
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Molecular weight: 300.14
Iso. SMILES: B1(C2=CC=CC=C2C=NN1S(=O)(=O)C3=CC=C(C=C3)C)O
InChI Key: UQIDNSKBUXCODH-UHFFFAOYSA-N
Can. SMILES: CC1=CC=C(C=C1)S(=O)(=O)N2B(C3=C(C=CC=C3)C=N2)O
InChI: InChI=1S/C14H13BN2O3S/c1-11-6-8-13(9-7-11)21(19,20)17-15(18)14-5-3-2-4-12(14)10-16-17/h2-10,18H,1H3
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/Diazaborine
Citations:
  • https://pubmed.ncbi.nlm.nih.gov/18193820/
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199504/
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666481/

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