Compound ID | 2137

Update compound information

Cerexin and analogues

Class: Lipopeptide

Spectrum of activity: Gram-positive
Details of activity: Disrupts the integrity of the outer membrane and leads to cell membrane permeation and disintegration.
Description: Natural product produced by Bacillus; cationic nonribosomal peptide, synthetic analogues
Year first mentioned: 1975
Development status: Experimental
Chemical structure(s):
Click here for structure editor
Molecular weight: 1374.58
Iso. SMILES: CC[C@@H](C)C(C(=O)O)NC(=O)C(CC1=CNC2=CC=CC=C21)NC(=O)C(CO)NC(=O)C([C@@H](C)O)NC(=O)C(CC(CCN)O)NC(=O)C(CC(=O)N)NC(=O)C(CC(=O)N)NC(=O)C(C(C)C)NC(=O)C(C(C)C)NC(=O)C(CC(=O)N)NC(=O)CC(CCCCCC(C)C)O
InChI Key: FJMFWIVNMAFUOP-MEIKFJLBSA-N
Can. SMILES: CC[C@@H](C)C(C(=O)O)NC(=O)C(CC1=CNC2=C1C=CC=C2)NC(=O)C(CO)NC(=O)C([C@@H](C)O)NC(=O)C(CC(CCN)O)NC(=O)C(CC(=O)N)NC(=O)C(CC(=O)N)NC(=O)C(C(C)C)NC(=O)C(C(C)C)NC(=O)C(CC(=O)N)NC(=O)CC(CCCCCC(C)C)O
InChI: InChI=1S/C63H103N15O19/c1-10-33(8)52(63(96)97)77-56(89)40(22-35-28-68-39-19-15-14-18-38(35)39)70-59(92)45(29-79)74-62(95)53(34(9)80)78-57(90)41(23-37(82)20-21-64)71-54(87)43(26-47(66)84)72-55(88)44(27-48(67)85)73-60(93)50(31(4)5)76-61(94)51(32(6)7)75-58(91)42(25-46(65)83)69-49(86)24-36(81)17-13-11-12-16-30(2)3/h14-15,18-19,28,30-34,36-37,40-45,50-53,68,79-82H,10-13,16-17,20-27,29,64H2,1-9H3,(H2,65,83)(H2,66,84)(H2,67,85)(H,69,86)(H,70,92)(H,71,87)(H,72,88)(H,73,93)(H,74,95)(H,75,91)(H,76,94)(H,77,89)(H,78,90)(H,96,97)/t33-,34-,36?,37?,40?,41?,42?,43?,44?,45?,50?,51?,52?,53?/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/3085083
Citations:
  • https://pubmed.ncbi.nlm.nih.gov/26465807/
  • https://www.jstage.jst.go.jp/article/antibiotics1968/28/10/28_10_764/_pdf/-char/en

    • AntibioticDB is supported by GARDP.

    If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

    The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.