Compound ID | 2138

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Laterosporulin and analogues

Class: Lipopeptide

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Disrupts the integrity of the outer membrane and leads to cell membrane permeation and disintegration.
Description: Natural product produced by Brevibacillus; cationic nonribosomal peptide, cyclic depsipeptides
Year first mentioned: 2012
Development status: Experimental
External links:
Citations:
  • https://pubchem.ncbi.nlm.nih.gov/#query=Laterosporulin
  • https://www.nature.com/articles/s41467-018-05781-6
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293901/
  • https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.13129

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